Unlike THC, which binds to CB₁ receptors to produce intoxicating effects, CBD binds to neither CB₁ nor CB₂ receptors. However, this does not mean that it does not impact them. Its interaction with the cannabinoid receptors is more complex and not yet entirely understood, but scientists are convinced that it does in some way influence both major cannabinoid receptors.^{[4] [6]}

What is more interesting about CBD is that it also interacts with a variety of other, non-cannabinoid receptors in our bodies. One of the most important receptors that CBD activates is the serotonin receptor known as 5-HT1A.^[2] This receptor binds serotonin, which is one of the four types of happiness hormones – the other three being oxytocin, dopamine and endorphins.

Since this receptor plays an important role in various mental health disorders, CBD can play an integral role in the all-natural treatment of various conditions, such as depression^[8], post-traumatic stress disorder^[7] and anxiety^[3]. It should be noted that CBD works well in combination with other cannabinoids, such as CBC, which increase its beneficial effects.^[5]

Another major non-cannabinoid receptor that CBD affects is the TPRV1 receptor.^[2] The TPRV1 receptor is responsible for managing inflammation and pain, which explains certain anti-inflammatory and analgesic effects of CBD.

CBD obtained from cannabis is commercially available in various forms that mostly differ from one another in the content of CBD and in the content of other substances, including different cannabinoids:

1. CBD can be safely consumed in its natural form – the flowers of the cannabis plant. However, if you decide to consume the flowers, make sure you consume varieties that contain little to no THC if you want to avoid its intoxicating effects.
2. CBD is also available as a CBD oil. This is the safest method for those who only want to consume CBD and want to avoid consuming other cannabinoids, which may have undesirable or conflicting effects. These oils come in a variety of different concentrations. Lower concentrations have mild effects and promote general well-being [a perfect source of general wellness can be a Well-Being Oil with 5% CBD]. Whereas higher concentrations are more potent and can reduce the level of stress and promote sleep [a 15% CBD Sweet Dreams Oil can be a perfect solution for relaxation and good-night sleep]. In addition, a mid concentration CBD oil may be both uplifting and relaxing [Good Mood Oil with 10%CBD].
3. Last but not least, CBD is also used as an active ingredient in various cosmetic, beauty and hygiene products:

• Massage oils, which can relieve muscle and joint pain and soothe the symptoms of PMS;
• Lubricants that intensify the most intimate pleasures;
• Hair products that promote the health of the scalp and hair;
• And many other products.

Now that you know all the basics about CBD and how it interacts with your body, you can easily learn more. In our next article, we will explore the health benefits of CBD in more detail. We will focus on those conditions where CBD has been studied extensively, such as acne, diabetes, cancer, depression. It has even been proven beneficial in treating substance addiction. Stay tuned!